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KMID : 0370919920090020396
Yeungnam Univercity Journal of Medicine
1992 Volume.9 No. 2 p.396 ~ p.406
Antimycotic Susceptibility Testing of Trichophyton Rubrum by Microculture Method




Abstract
Various susceptibility tests have been used to determine minimal inhibition concentration(MIC) of dermatophytes. They have limitations to apply practically because they need long time to determine MIC. Authors examined MIC of T. rubrum to
ketoconazole
and itraconazole using 96-well microplate and 24-well marcroplate by method of Granade and Artis and tried to check the possiblity of this method on clinical application.
@ES the results were as follows.
@EN 1. Effect of inoculation density on determination time and MIC: Determination of MIC were possible in 4th days after inoculation at higher inoculation density (aborbance 2.0, 1.0) compared to 6th days at lower inoculation density(absorbance
0.5,
0.25).
KEYWORD
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